Implication of functional activity for determining therapeutic efficacy of suicide genes in vitro

Author:

Gopinath P.,Ghosh Siddhartha Sankar

Publisher

Springer Science and Business Media LLC

Subject

General Medicine,Biotechnology,Bioengineering,Applied Microbiology and Biotechnology

Reference27 articles.

1. Bernt KM, Steinwaerder DS, Ni S et al (2002) Enzyme-activated prodrug therapy enhances tumor-specific replication of adenovirus vectors. Cancer Res 62:6089–6098

2. Chu RL, Post DE, Khuri FR et al (2004) Use of replicating oncolytic adenoviruses in combination therapy for cancer. Clin Cancer Res 10:5299–5312

3. Ghosh SS, Gopinath P, Ramesh A (2006) Adenoviral vectors: a promising tool for gene therapy. Appl Biochem Biotechnol 133:9–29

4. Gopinath P, Ghosh SS (2007) Monitoring green fluorescent protein for functional delivery of E. coli cytosine deaminase suicide gene and the effect of curcumin in vitro. Gene Ther Mol Biol 11:219–228

5. Gopinath P, Ghosh SS (2008) Apoptotic induction with bifunctional E. coli cytosine deaminase-uracil phosphoribosyltransferase mediated suicide gene therapy is synergized by curcumin treatment in vitro. Mol Biotechnol (DOI 10.1007/s12033-007-9026-3 )

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