Screening and heterologous expression of flavone synthase and flavonol synthase to catalyze hesperetin to diosmetin-Reference-Cited by-同舟云学术

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Screening and heterologous expression of flavone synthase and flavonol synthase to catalyze hesperetin to diosmetin

Published:2021-09-12 Issue:11 Volume:43 Page:2161-2183
ISSN:0141-5492
Container-title:Biotechnology Letters
language:en
Short-container-title:Biotechnol Lett

Author:

Wang Zhen,Huang Xu,Liu Juan,Xiao Feiyao,Tian Miaomiao,Ding Shenghua^ORCID,Shan Yang

Funder

Science and Technology Innovation Platform and Talent Plan of Hunan

Agricultural Science and Technology Innovation Fund of Hunan

Training Program for Excellent Young Innovators of Changsha

Special Project for Construction of Innovative Hunan Province

Agricultural Science and Technology Innovation Project of Hunan Province

Publisher

Springer Science and Business Media LLC

Subject

General Medicine,Biotechnology,Bioengineering,Applied Microbiology and Biotechnology

Link

https://link.springer.com/content/pdf/10.1007/s10529-021-03184-0.pdf

Reference42 articles.

1. Akashi T, Fukuchi-Mizutani M, Aoki T, Ueyama Y, Yonekura-Sakakibara K, Tanaka Y, Kusumi T, Ayabe S (1999) Molecular cloning and biochemical characterization of a novel cytochrome P450, flavone synthase II, that catalyzes direct conversion of flavanones to flavones. Plant Cell Physiol 40:1182–1186. https://doi.org/10.1016/j.jflm.2009.01.004

2. Britsch L (1990) Purification and characterization of flavone synthase I, a 2-oxoglutarate-dependent desaturase. Arch Biochem Biophys 282:152–160. https://doi.org/10.1016/0003-9861(90)90099-K

3. Cheng AX, Han XJ, Wu YF, Lou HX (2014) The function and catalysis of 2-oxoglutarate-dependent oxygenases involved in plant flavonoid biosynthesis. Int J Mol Sci 15:1080–1095. https://doi.org/10.3390/ijms15011080

4. Chua CS, Biermann D, Goo KS, Sim TS (2007) Elucidation of active site residues of Arabidopsis thaliana flavonol synthase provides a molecular platform for engineering flavonols. Phytochemistry 69:66–75. https://doi.org/10.1016/j.phytochem.2007.07.006

5. Davydov DR, Davydova NY, Sineva EV, Halpert JR (2015) Interactions among cytochromes p450 in microsomal membranes: oligomerization of cytochromes p450 3a4, 3a5, and 2e1 and its functional consequences. J Biol Chem 290:3850–3864. https://doi.org/10.1074/jbc.M114.615443

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3. Substrates and Loaded Iron Ions Relative Position Influence the Catalytic Characteristics of the Metalloenzymes Angelica archangelica Flavone Synthase I and Camellia sinensis Flavonol Synthase;Frontiers in Pharmacology;2022-06-08

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