Population stratification may bias analysis of PGC-1α as a modifier of age at Huntington disease motor onset-Reference-Cited by-同舟云学术

Population stratification may bias analysis of PGC-1α as a modifier of age at Huntington disease motor onset

Published:2012-07-25 Issue:12 Volume:131 Page:1833-1840
ISSN:0340-6717
Container-title:Human Genetics
language:en
Short-container-title:Hum Genet

Author:

Ramos Eliana Marisa,Latourelle Jeanne C.,Lee Ji-Hyun,Gillis Tammy,Mysore Jayalakshmi S.,Squitieri Ferdinando,Di Pardo Alba,Di Donato Stefano,Hayden Michael R.,Morrison Patrick J.,Nance Martha,Ross Christopher A.,Margolis Russell L.,Gomez-Tortosa Estrella,Ayuso Carmen,Suchowersky Oksana,Trent Ronald J.,McCusker Elizabeth,Novelletto Andrea,Frontali Marina,Jones Randi,Ashizawa Tetsuo,Frank Samuel,Saint-Hilaire Marie-Helene,Hersch Steven M.,Rosas Herminia D.,Lucente Diane,Harrison Madaline B.,Zanko Andrea,Marder Karen,Gusella James F.,Lee Jong-Min,Alonso Isabel,Sequeiros Jorge,Myers Richard H.,MacDonald Marcy E.

Publisher

Springer Science and Business Media LLC

Subject

Genetics(clinical),Genetics

Link

http://link.springer.com/content/pdf/10.1007/s00439-012-1205-z

Reference28 articles.

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2. Che HV, Metzger S, Portal E, Deyle C, Riess O, Nguyen HP (2011) Localization of sequence variations in PGC-1alpha influence their modifying effect in Huntington disease. Mol Neurodegener 6(1):1. doi: 10.1186/1750-1326-6-1

3. Cui L, Jeong H, Borovecki F, Parkhurst CN, Tanese N, Krainc D (2006) Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration. Cell 127(1):59–69. doi: 10.1016/j.cell.2006.09.015

4. Di Maria E, Marasco A, Tartari M, Ciotti P, Abbruzzese G, Novelli G, Bellone E, Cattaneo E, Mandich P (2006) No evidence of association between BDNF gene variants and age-at-onset of Huntington’s disease. Neurobio Dis 24(2):274–279. doi: 10.1016/j.nbd.2006.07.002

5. Duyao M, Ambrose C, Myers R, Novelletto A, Persichetti F, Frontali M, Folstein S, Ross C, Franz M, Abbott M, Gray J, Conneally P, Young A, Penney J, Hollingsworth Z, Shoulson I, Lazzarini A, Falek A, Koroshetz W, Sax D, Bird E, Vonsattel J, Bonilla E, Alvir J, Bickham Conde J, Cha J-H, Dure L, Gomez F, Ramos M, Sanchez-Ramos J, Snodgrass S, de Young M, Wexler N, Moscowitz C, Penchaszadeh G, MacFarlane H, Anderson M, Jenkins B, Srinidhi J, Barnes G, Gusella JF, MacDonald M (1993) Trinucleotide repeat length instability and age of onset in Huntington’s disease. Nat Genet 4(4):387–392. doi: 10.1038/ng0893-387

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