Genome-wide association study identifies a PSMD3 variant associated with neutropenia in interferon-based therapy for chronic hepatitis C

Author:

Iio Etsuko,Matsuura Kentaro,Nishida Nao,Maekawa Shinya,Enomoto Nobuyuki,Nakagawa Mina,Sakamoto Naoya,Yatsuhashi Hiroshi,Kurosaki Masayuki,Izumi Namiki,Hiasa Yoichi,Masaki Naohiko,Ide Tatsuya,Hino Keisuke,Tamori Akihiro,Honda Masao,Kaneko Shuichi,Mochida Satoshi,Nomura Hideyuki,Nishiguchi Shuhei,Okuse Chiaki,Itoh Yoshito,Yoshiji Hitoshi,Sakaida Isao,Yamamoto Kazuhide,Watanabe Hisayoshi,Hige Shuhei,Matsumoto Akihiro,Tanaka Eiji,Tokunaga Katsushi,Tanaka Yasuhito

Publisher

Springer Science and Business Media LLC

Subject

Genetics (clinical),Genetics

Reference25 articles.

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3. Fellay J, Thompson AJ, Ge D, Gumbs CE, Urban TJ, Shianna KV, Little LD, Qiu P, Bertelsen AH, Watson M, Warner A, Muir AJ, Brass C, Albrecht J, Sulkowski M, McHutchison JG, Goldstein DB (2010) ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C. Nature 464:405–408. doi: 10.1038/nature08825

4. Ge D, Fellay J, Thompson AJ, Simon JS, Shianna KV, Urban TJ, Heinzen EL, Qiu P, Bertelsen AH, Muir AJ, Sulkowski M, McHutchison JG, Goldstein DB (2009) Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature 461:399–401. doi: 10.1038/nature08309

5. George SL, Bacon BR, Brunt EM, Mihindukulasuriya KL, Hoffmann J, Di Bisceglie AM (2009) Clinical, virologic, histologic, and biochemical outcomes after successful HCV therapy: a 5-year follow-up of 150 patients. Hepatology 49:729–738. doi: 10.1002/hep.22694

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