Autosomal recessive mental retardation: homozygosity mapping identifies 27 single linkage intervals, at least 14 novel loci and several mutation hotspots

Author:

Kuss Andreas Walter,Garshasbi Masoud,Kahrizi Kimia,Tzschach Andreas,Behjati Farkhondeh,Darvish Hossein,Abbasi-Moheb Lia,Puettmann Lucia,Zecha Agnes,Weißmann Robert,Hu Hao,Mohseni Marzieh,Abedini Seyedeh Sedigheh,Rajab Anna,Hertzberg Christoph,Wieczorek Dagmar,Ullmann Reinhard,Ghasemi-Firouzabadi Saghar,Banihashemi Susan,Arzhangi Sanaz,Hadavi Valeh,Bahrami-Monajemi Gholamreza,Kasiri Mahboubeh,Falah Masoumeh,Nikuei Pooneh,Dehghan Atefeh,Sobhani Masoumeh,Jamali Payman,Ropers Hans Hilger,Najmabadi Hossein

Publisher

Springer Science and Business Media LLC

Subject

Genetics(clinical),Genetics

Reference33 articles.

1. Abbasi Moheb L, Jensen LR, Garshasbi M, Kahrizi K, Ghadami S, Wrogemann K, Hu H, Kariminejad R, Behjati F, Mohseni M, Falah M, Khodai H, Kasiri M, Darvish H, Tzschach A, Ropers HH, Najmabadi H, Kuss AW (2009) Two independent mutations in the ZNF526 gene are associated with non-syndromic autosomal recessive mental retardation. In: Annual meeting of the American Society for Human Genetics, Honolulu, Hawaii

2. Al-Ansari A (1993) Etiology of mild mental retardation among Bahraini children: a community-based case control study. Ment Retard 31:140–143

3. Basel-Vanagaite L, Attia R, Yahav M, Ferland RJ, Anteki L, Walsh CA, Olender T, Straussberg R, Magal N, Taub E, Drasinover V, Alkelai A, Bercovich D, Rechavi G, Simon AJ, Shohat M (2006) The CC2D1A, a member of a new gene family with C2 domains, is involved in autosomal recessive non-syndromic mental retardation. J Med Genet 43:203–210

4. Bittles A (2001) Consanguinity and its relevance to clinical genetics. Clin Genet 60:89–98

5. Bittles AH, Neel JV (1994) The costs of human inbreeding and their implications for variations at the DNA level. Nat Genet 8:117–121

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