Heat increases full-length SMN splicing: promise for splice-augmenting therapies for SMA
Author:
Funder
national institute of neurological disorders and stroke
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics
Link
https://link.springer.com/content/pdf/10.1007/s00439-021-02408-7.pdf
Reference86 articles.
1. Al-Fageeh MB, Smales CM (2006) Control and regulation of the cellular responses to cold shock: the responses in yeast and mammalian systems. Biochem J 397:247–259
2. Al-Fageeh MB, Smales CM (2009) Cold-inducible RNA binding protein (CIRP) expression is modulated by alternative mRNAs. RNA (new York, N.y) 15:1164–1176
3. Ars E, Serra E, de la Luna S, Estivill X, Lazaro C (2000) Cold shock induces the insertion of a cryptic exon in the neurofibromatosis type 1 (NF1) mRNA. Nucleic Acids Res 28:1307–1312
4. Bebee TW, Dominguez CE, Samadzadeh-Tarighat S, Akehurst KL, Chandler DS (2012) Hypoxia is a modifier of SMN2 splicing and disease severity in a severe SMA mouse model. Hum Mol Genet 21:4301–4313
5. Bertini E, Dessaud E, Mercuri E, Muntoni F, Kirschner J, Reid C, Lusakowska A, Comi GP, Cuisset JM, Abitbol JL et al (2017) Safety and efficacy of olesoxime in patients with type 2 or non-ambulatory type 3 spinal muscular atrophy: a randomised, double-blind, placebo-controlled phase 2 trial. Lancet Neurol 16:513–522
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