Four New Limonoids from the Barks of Toona ciliata-Reference-Cited by-同舟云学术

Four New Limonoids from the Barks of Toona ciliata

Published:2020-10-23 Issue:1 Volume:11 Page:81-86
ISSN:2192-2195
Container-title:Natural Products and Bioprospecting
language:en
Short-container-title:Nat. Prod. Bioprospect.

Author:

Zhang Pan-Pan,Bu Yun-Ge,Xue Shang,Cui Zhi-Rong,Tang Peng-Fei,Luo Jun,Kong Ling-Yi

Abstract

Abstract Four new limonoids, toonayunnanaes F − I (1 − 4), and six known compounds (5 − 10) were isolated from the barks of Toona ciliata. Their structures were elucidated by thoroughly analyzing of NMR and HRMS data, and single-crystal X-ray diffraction of 1. The oxetane ring moiety in 1 was rare in limonoids and other natural products. Compound 1 showed nitric oxide (NO) inhibitory effect with an IC50 38.45 ± 0.41 µM in lipopolysaccharide (LPS)-activated RAW 264.7 macrophages. Graphic Abstract

Funder

National Natural Science Foundation of China

National New Drug Innovation Major Project

National Key R&D Program of China

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,Plant Science,Pharmacology,Toxicology,Biochemistry,Food Science,Analytical Chemistry

Link

http://link.springer.com/content/pdf/10.1007/s13659-020-00274-w.pdf

Reference19 articles.

1. C.Y. Wu, Index Florae Yunnanensis (I) (The People’s Publishing House, Yunnan, 1984), pp. 832–833

2. S.K. Chen, B.Y. Chen, H. Li, In Flora Reipublicae Popularis Sinicae (ZhongguoZhiwu Zhi), 43(3) (Science Press, Beijing, 1997), pp. 239−240

3. Chinese Materia Medica (Zhonghua Benchao), vol 5 (Shanghai Science and Technology, Shanghai, 1999); pp. 44−45

4. F. Zhang, J.S. Wang, Y.C. Gu, L.Y. Kong, J. Nat. Prod. 75, 538–546 (2012)

5. M.S. Yang, S.M. Hu, L.Y. Kong, J. Luo, Tetrahedron 71, 8472–8477 (2015)

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Antimalarial activity of Toona ciliata MJ Roem aqueous methanolic leaf extract and its antioxidant and phytochemical properties;Journal of Traditional and Complementary Medicine;2023-11

2. Four-membered ring systems;Progress in Heterocyclic Chemistry;2023

3. Tociliatonoid A: A novel limonoid from Toona ciliata;Tetrahedron Letters;2022-12

4. Isolation and Bioactivities of Limonoids from Meliaceae Family: A Review;Current Organic Chemistry;2022-07

5. Research progress of meliaceous limonoids from 2011 to 2021;Natural Product Reports;2022