Abstract
AbstractFive new toosendanin limonoids with highly oxidative furan ring walsurobustones A-D (1–4), and one new furan ring degraded limonoid walsurobustone E (5) together with one known compound toonapubesic acid B (6) were isolated from the leaves of Walsura robusta. Their structures were elucidated by NMR and MS data. Especially, the absolute configuration of toonapubesic acid B (6) was confirmed by X-ray diffraction study. Compounds 1–6 exhibited good cytotoxicity against the cancer cell lines HL-60, SMMC-7721, A-549, MCF-7, and SW480.
Funder
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,Plant Science,Pharmacology,Toxicology,Biochemistry,Food Science,Analytical Chemistry
Reference18 articles.
1. Luo J, Sun YP, Li QR, Kong LY. Research progress of meliaceous limonoids from 2011 to 2021. Nat Prod Rep. 2022;39:1325–65.
2. Tan QG, Luo XD. Meliaceous limonoids: chemistry and biological activities. Chem Rev. 2011;111:7437–522.
3. Peng H, Mabberley DJ. Flora of China. 2008;11:119–20.
4. Luo XD, Wu SH, Ma YB, Wu DG. Tetranortriterpenoids from Walsura yunnanensis. J Nat Prod. 2000;63:947–51.
5. Balakrishna K, Rao RB, Patra A, Ali SU. Constituents of Walsura piscidia. Fitoterapia. 1995;66:548.
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献