Estimand Framework and Statistical Considerations for Integrated Analysis of Clinical Trial Safety Data

Author:

Hedman Katarina,Kordzakhia George,Li Hongjian,Nyström Per

Publisher

Springer Science and Business Media LLC

Reference24 articles.

1. US Food and Drug Administration, Draft Guidance for Industry. Meta-Analyses of randomized controlled clinical trials to evaluate the safety of human drugs or biological products. 2018; https://www.fda.gov/regulatory-information/search-fda-guidance-documents/meta-analyses-randomized-controlled-clinical-trials-evaluate-safety-human-drugs-or-biological

2. US Food and Drug Administration, Guidance for Industry. Premarketing risk assessment. 2005; https://www.fda.gov/regulatory-information/search-fda-guidance-documents/premarketing-risk-assessment

3. Crowe BJ, Xia HA, Berlin JA, et al. Recommendations for safety planning, data collection, evaluation and reporting during drug, biologic and vaccine development: a report of the safety planning, evaluation, and reporting team. Clin Trials. 2009;6:430–40.

4. Berlin JA, Crowe BJ, Whalen E, et al. Meta-analysis of clinical trial safety data in a drug development program: answers to frequently asked questions. Clin Trials. 2013;10(1):20–31.

5. Simpson EH. The interpretation of interaction in contingency tables. J R Stat. 1951;13(2):238–41.

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