Comparison Between Simultaneous and Sequential Utilization of Safety and Efficacy for Optimal Dose Determination in Bayesian Model-Assisted Designs
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Public Health, Environmental and Occupational Health,Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
Link
https://link.springer.com/content/pdf/10.1007/s43441-023-00517-1.pdf
Reference33 articles.
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2. Ivanova A. A new dose-finding design for bivariate outcomes. Biometrics. 2003;59(4):1001–7.
3. Dragalin V, Fedorov V. Adaptive designs for dose-finding based on efficacy–toxicity response. J Stat Plan Inference. 2006;136(6):1800–23.
4. FDA (2018) Expansion cohorts: Use in first-in-human clinical trials to expedite development of oncology drugs and biologics guidance for industry. URL:https://www.fda.gov/media/115172/download.
5. O’Quigley J. Sequential monitoring of Phase I dose expansion cohorts. Stat Med. 2017;36(2):204–14.
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