11C-ORM-13070, a novel PET ligand for brain α2C-adrenoceptors: radiometabolism, plasma pharmacokinetics, whole-body distribution and radiation dosimetry in healthy men-Reference-Cited by-同舟云学术

11C-ORM-13070, a novel PET ligand for brain α2C-adrenoceptors: radiometabolism, plasma pharmacokinetics, whole-body distribution and radiation dosimetry in healthy men

Published:2014-05-17 Issue:10 Volume:41 Page:1947-1956
ISSN:1619-7070
Container-title:European Journal of Nuclear Medicine and Molecular Imaging
language:en
Short-container-title:Eur J Nucl Med Mol Imaging

Author:

Luoto Pauliina,Suilamo Sami,Oikonen Vesa,Arponen Eveliina,Helin Semi,Herttuainen Jukka,Hietamäki Johanna,Holopainen Aila,Kailajärvi Marita,Peltonen Juha M.,Rouru Juha,Sallinen Jukka,Scheinin Mika,Virta Jere,Virtanen Kirsi,Volanen Iina,Roivainen Anne,Rinne Juha O.

Publisher

Springer Science and Business Media LLC

Subject

Radiology, Nuclear Medicine and imaging,General Medicine,Radiology, Nuclear Medicine and imaging,General Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00259-014-2782-y.pdf

Reference16 articles.

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3. Scheibner J, Trendelenburg AU, Hein L, Starke K. Alpha2-adrenoceptors modulating neuronal serotonin release: a study in alpha2-adrenoceptor subtype-deficient mice. Br J Pharmacol. 2001;132:925–33.

4. Knaus AE, Muthig V, Schickinger S, Moura E, Beetz N, Gilsbach R, et al. Alpha2-adrenoceptor subtypes – unexpected functions for receptors and ligands derived from gene-targeted mouse models. Neurochem Int. 2007;51:277–81.

5. Holmberg M, Fagerholm V, Scheinin M. Regional distribution of alpha(2C)-adrenoceptors in brain and spinal cord of control mice and transgenic mice overexpessing the alpha(2C)-subtype: an autoradiographic study with [3H]RX821002 and [3H]rauwolscine. Neuroscience. 2003;117:875–98.

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