Preclinical evaluation of [99mTc]Tc-labeled anti-EpCAM nanobody for EpCAM receptor expression imaging by immuno-SPECT/CT-Reference-Cited by-同舟云学术

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Preclinical evaluation of [99mTc]Tc-labeled anti-EpCAM nanobody for EpCAM receptor expression imaging by immuno-SPECT/CT

Published:2022-01-11 Issue:6 Volume:49 Page:1810-1821
ISSN:1619-7070
Container-title:European Journal of Nuclear Medicine and Molecular Imaging
language:en
Short-container-title:Eur J Nucl Med Mol Imaging

Author:

Liu Tianyu,Wu Yue,Shi Linqing,Li Liqiang,Hu Biao,Wang Yanpu,Gao Hannan,Yu Xiaolu,Zhang Xin,Zhao Huiyun,Wan Yakun,Jia Bing,Wang Fan

Funder

Key Technologies Research and Development Program

National Natural Science Foundation of China

Publisher

Springer Science and Business Media LLC

Subject

Radiology, Nuclear Medicine and imaging,General Medicine,Radiology, Nuclear Medicine and imaging,General Medicine

Link

https://link.springer.com/content/pdf/10.1007/s00259-021-05670-z.pdf

Reference28 articles.

1. Baeuerle P, Gires O. EpCAM (CD326) finding its role in cancer. Br J Cancer. 2007;96:417–23.

2. Litvinov S, Balzar M, Winter M, Bakker H, Briaire-de Bruijn I, Prins F, et al. Epithelial cell adhesion molecule (Ep-CAM) modulates cell-cell interactions mediated by classic cadherins. J Cell Biol. 1997;139:1337–48.

3. Went P, Lugli A, Meier S, Bundi M, Mirlacher M, Sauter G, et al. Frequent EpCam protein expression in human carcinomas. Hum Pathol. 2004;35:122–8.

4. Went P, Vasei M, Bubendorf L, Terracciano L, Tornillo L, Riede U, et al. Frequent high-level expression of the immunotherapeutic target Ep-CAM in colon, stomach, prostate and lung cancers. Br J Cancer. 2006;94:128–35.

5. Spizzo G, Went P, Dirnhofer S, Obrist P, Moch H, Baeuerle P, et al. Overexpression of epithelial cell adhesion molecule (Ep-CAM) is an independent prognostic marker for reduced survival of patients with epithelial ovarian cancer. Gynecol Oncol. 2006;103:483–8.

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