Prescription Opioid Dose Reductions and Potential Adverse Events: a Multi-site Observational Cohort Study in Diverse US Health Systems

Author:

Metz Verena E.,Ray G. Thomas,Palzes Vanessa,Binswanger Ingrid,Altschuler Andrea,Karmali Ruchir N.,Ahmedani Brian K.,Andrade Susan E.,Boscarino Joseph A.,Clark Robin E.,Haller Irina V.,Hechter Rulin C.,Roblin Douglas W.,Sanchez Katherine,Bailey Steffani R.,McCarty Dennis,Stephens Kari A.,Rosa Carmen L.,Rubinstein Andrea L.,Campbell Cynthia I.

Funder

National Institute on Drug Abuse

National Drug Abuse Treatment Clinical Trials Network

Publisher

Springer Science and Business Media LLC

Subject

Internal Medicine

Reference37 articles.

1. The Lancet. A time of crisis for the opioid epidemic in the USA [editorial]. Lancet. 2021;398(10297):277.

2. Drug overdose deaths in the U.S. top 100,000 annually. Centers for Disease Control and Prevention, National Center for Health Statistics. Last reviewed November 2021. Available at: https://www.cdc.gov/nchs/pressroom/nchs_press_releases/2021/20211117.htm. Accessed September 26, 2023.

3. Dahlhamer JM, Connor EM, Bose J, Lucas JL, Zelaya CE. Prescription opioid use among adults with chronic pain: United States, 2019. Natl Health Stat Report. 2021;162:1-9.

4. De Sola H, Duenas M, Salazar A, Ortega-Jimenez P, Failde I. Prevalence of therapeutic use of opioids in chronic non-cancer pain patients and associated factors: a systematic review and meta-analysis. Front Pharmacol. 2020;11:564412.

5. Groenewald CB, Murray CB, Battaglia M, Scaini S, Quinn PD. Prevalence of pain management techniques among adults with chronic pain in the United States, 2019. JAMA Netw Open. 2022;5(2):e2146697.

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