Common Germinal-Center B-Cell Origin of the Malignant Cells in Two Composite Lymphomas, Involving Classical Hodgkin’s Disease and Either Follicular Lymphoma or B-CLL-Reference-Cited by-同舟云学术

Common Germinal-Center B-Cell Origin of the Malignant Cells in Two Composite Lymphomas, Involving Classical Hodgkin’s Disease and Either Follicular Lymphoma or B-CLL

Published:2001-05 Issue:5 Volume:7 Page:285-292
ISSN:1076-1551
Container-title:Molecular Medicine
language:en
Short-container-title:Mol Med

Author:

Küppers Ralf,Sousa Ana B.,Baur Audrey S.,Strickler John G.,Rajewsky Klaus,Hansmann Martin-Leo

Publisher

Springer Science and Business Media LLC

Subject

Genetics (clinical),Genetics,Molecular Biology,Molecular Medicine

Link

http://link.springer.com/content/pdf/10.1007/BF03402211.pdf

Reference26 articles.

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2. Klein U, Goossens T, Fischer M, et al. (1998) Somatic hypermutation in normal and transformed human B cells. Immunol. Rev. 162: 261–280.

3. Kanzler H, Küppers R, Hansmann ML, Rajewsky K. (1996) Hodgkin and Reed-Sternberg cells in Hodgkin’s disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells. J. Exp. Med. 184: 1495–1505.

4. Küppers R, Rajewsky K. (1998) The origin of Hodgkin and Reed/Sternberg cells in Hodgkin’s disease. Annu. Rev. Immunol. 16: 471–493.

5. Marafioti T, Hummel M, Foss H-D, et al. (2000) Hodgkin and Reed-Sternberg cells represent an expansion of a single clone originating from a germinal center B-cell with functional immunoglobulin gene rearrangements but defective immunoglobulin transcription. Blood 95: 1443–1450.

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