Variability of 6-mercaptopurine pharmacokinetics during oral maintenance therapy of children with acute leukemia
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology
Link
https://link.springer.com/content/pdf/10.1007/BF02985158.pdf
Reference43 articles.
1. Burchenal J H, Murphy M L, Ellison R R: Clinical evaluation of a new antimetabolite, 6-mercaptopurine, in the treatment of acute leukemia and allied disease.Blood 8, 965 (1953).
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3. Poplack D G, Balis F M, Zimm S: The pharmacology of orally administered chemotherapy: a reappraisal.Cancer 58, 473 (1986).
4. Elion G B, Callahan S, Nathan H, Bieber S, Rundles R, Hitchings G H: Potentiation by inhibition of drug degradation: 6-substituted purines and xanthine oxidase.Biochem Pharmac 12, 85 (1963).
5. Zimm S, Collins J M, Riccardi R, O’Neil D, Narang P K, Chabner B, Poplack D B: Variable bioavailability of oral mercaptopurine.New Engl J Med 308, 1005 (1983a).
Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. The degree of myelosuppression during maintenance therapy of adolescents with B-lineage intermediate risk acute lymphoblastic leukemia predicts risk of relapse;Leukemia;2010-02-04
2. Intraindividual variation in 6-mercaptopurine pharmacokinetics during oral maintenance therapy of children with acute lymphoblastic leukaemia;European Journal of Clinical Pharmacology;1991-06
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