A Molecular Aspect in the Regulation of Drug Metabolism: Does PXR-Induced Enzyme Expression Always Lead to Functional Changes in Drug Metabolism?-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

A Molecular Aspect in the Regulation of Drug Metabolism: Does PXR-Induced Enzyme Expression Always Lead to Functional Changes in Drug Metabolism?

Published:2016-05-04 Issue:4 Volume:2 Page:187-192
ISSN:2198-641X
Container-title:Current Pharmacology Reports
language:en
Short-container-title:Curr Pharmacol Rep

Author:

Wei Yuan,Tang Chenxiao,Sant Vinayak,Li Song,Poloyac Samuel M.,Xie Wen

Funder

National Institutes of Health

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology,Genetics,Biochemistry

Link

http://link.springer.com/content/pdf/10.1007/s40495-016-0062-1.pdf

Reference61 articles.

1. Xie W et al. Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR. Genes Dev. 2000;14:3014–23.

2. Gao J, Xie W. Pregnane X receptor and constitutive androstane receptor at the crossroads of drug metabolism and energy metabolism. Drug Metab Dispos. 2010;38:2091–5.

3. Jancova P, Anzenbacher P, Anzenbacherova E. Phase II drug metabolizing enzymes. Biomed Pap. 2010;154:103–16.

4. Kliewer SA et al. An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway. Cell. 1998;92:73–82.

5. Blumberg B et al. SXR, a novel steroid and xenobiotic-sensing nuclear receptor. Genes Dev. 1998;12:3195–205.

Cited by 21 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Generation and characterization of cytochrome P450 3A74 CRISPR/Cas9 knockout bovine foetal hepatocyte cell line (BFH12);Biochemical Pharmacology;2024-06

2. Induction of human hepatic cytochrome P-450 3A4 expression by antifungal succinate dehydrogenase inhibitors;Ecotoxicology and Environmental Safety;2024-05

3. Effects of aqueous extract from Baiyedancong-Oolong tea on cytochrome P450 enzymes activities, P-gp and OATs transport abilities and transcription levels in mice;Frontiers in Nutrition;2023-05-09

4. The effects of hexabromocyclododecane on the transcriptome and hepatic enzyme activity in three human HepaRG-based models;Toxicology;2023-02

5. In Vitro Metabolism and CYP-Modulating Activity of Lavender Oil and Its Major Constituents;Molecules;2023-01-12

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3