The Utility of Pharmacometric Models in Clinical Pharmacology Research in Infants
Author:
Funder
NIH
National Institutes of Health
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,Genetics,Biochemistry
Link
https://link.springer.com/content/pdf/10.1007/s40495-020-00234-5.pdf
Reference36 articles.
1. Ward RM, Sherwin CM. Newborns still lack drug data to guide therapy. Br J Clin Pharmacol. 2016;82(6):1410–1. https://doi.org/10.1111/bcp.13074.
2. Giacoia GP, Mattison DR. Newborns and drug studies: the NICHD/FDA newborn drug development initiative. Clin Ther. 2005;27(6):796–813. https://doi.org/10.1016/j.clinthera.2005.06.008.
3. Best Pharmaceuticals for Children Act. 2002 (PLAW-107pubI109.pdf).
4. Pediatric Research Equity Act of 2003 (https://www.congress.gov/bill/108th-congress/senate-bill/650).
5. Ward RM, Benjamin DK Jr, Davis JM, Gorman RL, Kauffman R, Kearns GL, et al. The need for pediatric drug development. J Pediatr. 2018;192:13–21. https://doi.org/10.1016/j.jpeds.2017.08.011This article is an excellent review paper. It provides the major changes in the study of drugs in children and highlighted the need on pediatric drug development.
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