Biomarkers from Secondary Complications in Spinal Cord Injury
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,Genetics,Biochemistry
Link
https://link.springer.com/content/pdf/10.1007/s40495-021-00268-3.pdf
Reference54 articles.
1. Ahuja CS, Nori S, Tetreault L, Wilson J, Kwon B, Harrop J, et al. Traumatic spinal cord injury-repair and regeneration. Neurosurgery. 2017;80(3S):S9–22. https://doi.org/10.1093/neuros/nyw080.
2. •• Albayar AA, Roche A, Swiatkowski P, Antar S, Ouda N, Emara E, et al. Biomarkers in spinal cord injury: prognostic insights and future potentials. Front Neurol. 2019;10:27. https://doi.org/10.3389/fneur.2019.00027. This article provides a review of traumatic spinal cord injury in terms of consequences and its long term outlook. This article also describes common complications of SCI as well.
3. Leister I, Haider T, Mattiassich G, Kramer JLK, Linde LD, Pajalic A, et al. Biomarkers in traumatic spinal cord injury-technical and clinical considerations: a systematic review. Neurorehabil Neural Repair. 2020;34(2):95–110. https://doi.org/10.1177/1545968319899920.
4. • Wong KR, Mychasiuk R, O’Brien TJ, Shultz SR, McDonald SJ, Brady RD. Neurological heterotopic ossification: novel mechanisms, prognostic biomarkers and prophylactic therapies. Bone Res. 2020;8(1):42. https://doi.org/10.1038/s41413-020-00119-9. This article discusses NHO as a complication in that it provides a background and multiple viable biomarkers. This article also provides a recommendation for a therapeutic target to decrease NHO.
5. •• Alexander KA, Tseng HW, Fleming W, Jose B, Salga M, Kulina I, et al. Inhibition of JAK1/2 tyrosine kinases reduces neurogenic heterotopic ossification after spinal cord injury. Front Immunol. 2019;10:377. https://doi.org/10.3389/fimmu.2019.00377. This article provides a detailed explanation of causes for NHO. The article also describes therapeutic targets that could be further studied in order to mitigate this particular complication.
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