Challenges of Antibody Drug Conjugates in Cancer Therapy: Current Understanding of Mechanisms and Future Strategies
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,Genetics,Biochemistry
Link
http://link.springer.com/article/10.1007/s40495-018-0122-9/fulltext.html
Reference104 articles.
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3. Leyland-Jones B. Trastuzumab: hopes and realities. Lancet Oncol. 2002;3(3):137–44. https://doi.org/10.1016/S1470-2045(02)00676-9 .
4. Carter PJ, Senter PD. Antibody-drug conjugates for cancer therapy. Cancer J. 2008;14(3):154–69. https://doi.org/10.1097/PPO.0b013e318172d704 .
5. •• Beck A, Goetsch L, Dumontet C, Corvaia N. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315–37. https://doi.org/10.1038/nrd.2016.268 . This article provides a up-to-date review of current progress in ADCs and discussed strategies for the new waves of ADCs.
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