Noninvasive Dynamic Fluorescence Imaging of Human Melanomas Reveals that Targeted Inhibition of bFGF or FGFR-1 in Melanoma Cells Blocks Tumor Growth by Apoptosis

Author:

Valesky Marianne,Spang Aaron J.,Fisher Gregory W.,Farkas Daniel L.,Becker Dorothea

Publisher

Springer Science and Business Media LLC

Subject

Genetics(clinical),Genetics,Molecular Biology,Molecular Medicine

Reference18 articles.

1. Halaban R, Kwon BS, Ghosh S, Delli-Bovi P, Baird A. (1988) bFGF as an autocrine growth factor for human melanomas. Oncogene Res. 3: 177–186.

2. Becker D, Meier CB, Herlyn M. (1989) Proliferation of human malignant melanomas is inhibited by antisense oligodeoxynucleotides targeted against basic fibroblast growth factor. EMBO J. 8: 3685–3691.

3. Becker D, Lee PL, Rodeck U, Herlyn M. (1992) Inhibition of the fibroblast growth factor receptor 1 (FGFR-1) gene in human melanocytes and malignant melanomas leads to inhibition of proliferation and signs indicative of differentiation. Oncogene 7: 2302–2313.

4. Wang Y, Becker D. (1997) Antisense targeting of bFGF/FGFR-1 in human melanomas inhibits intratumoral angiogenesis and tumor growth. Nat. Med. 3: 887–893.

5. Mujumdar RB, Ernst LA, Mujumdar SR, Lewis CJ, Waggoner AS. (1993) Cyanine labeling reagents: Sulfoindocyanine succinimidyl esters. Bioconjugate Chem. 4: 105–108.

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