Potent Induction of Apoptosis by β-Lapachone in Human Multiple Myeloma Cell Lines and Patient Cells

Author:

Li Youzhi,Li Chiang J.,Yu Donghui,Pardee Arthur B.

Publisher

Springer Science and Business Media LLC

Subject

Genetics(clinical),Genetics,Molecular Biology,Molecular Medicine

Reference25 articles.

1. Treon SP, Teoh G, Urashima M, Ogata A, Chauhan D, Webb J, Anderson K. (1998) Antiestrogens induce apoptosis of multiple myeloma cells. Blood 92: 1749–1757.

2. Anderson K, Kyle RA, Berenson JR, Dalton WS.(1999) Recent Advances in the Biology and Treatment of Multiple Myeloma. Annual Meeting Report 1999.

3. Hooker SC. (1936) Lomatiol. Part II. Its occurence, constitution, relation to and conversion into lapachol. Also a synthesis of lapachol J. Am. Chem. Soc. 58: 1181–1190.

4. Goncalves de Lima O, D’Albuquerque IL, Goncalves de Lima C, Dalla Maia MH. (1962) Substancias antimicrobianas de plantas superiores. Rev. Inst. Antibiot. Univ. Recife. 4: 3–17.

5. Li CJ, Averboukh L, Pardee AB. (1993) Betalapachone, a novel DNA topoisomerase I inhibitor with a mode of action different from camptothecin. J. Biol. Chem. 268: 22463–22468.

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