Induction and Suppression of an Autoimmune Disease by Oligomerized T Cell Epitopes: Enhanced In Vivo Potency of Encephalitogenic Peptides

Author:

Falk K.,Rötzschke O.,Santambrogio L.,Dorf M. E.,Brosnan C.,Strominger J. L.

Publisher

Springer Berlin Heidelberg

Reference46 articles.

1. Rötzschke O, Falk K, Strominger JL (1997) Superactivation of an immune response triggered by oligomerized T cell epitopes. Proc Natl Acad Sci USA 94:14642–14647

2. Martin R and McFarland H (1996) Experimental immunotherapies for multiple sclerosis. Springer Semin Immunopathol 18:1–24

3. McFarlin DE, Blank SE, Kibler RF, McKneally S, Shapira R (1973) Experimental allergic encephalomyelitis in the rat: response to encephalitogenic proteins and peptides. Science 179:478–480

4. Tuohy VK, Lu Z, Sobel RA, Laursen RA, Lees MB (1989) Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice. J Immunol 142:1523–1527

5. Greer JM, Kuchroo VK, Sobel RA, Lees MB (1992) Identification and characterization of a second encephalitogenic determinant of myelin proteolipid protein (residues 178–191) for SJL mice. J Immunol 149:783–788

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