1. Theory, methods and application;G Klebe,1993
2. Langer T, Hoffmann RD (2006) Methods and principles in medicinal chemistry. In: Mannhold R, Kubinyi H, Folkers G (eds) Pharmacophores and pharmacophore searches, vol 32. Wiley-VCH, Weinheim
3. Marshall GR (1989) Computer-aided drug design. In: Richards WG (ed) Computer-aided molecular design. IBC Technical Services, London, pp 91–104
4. Bolin JT, Filman DJ, Matthews DA, Hamlin RC, Kraut J (1982) Crystal structure of Eschericha coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 Å resolution. J Biol Chem 257(13):13650–13662
5. Kearsley SK, Smith GM (1990) An alternative method for the alignment of molecular structures: maximizing electrostatic and steric overlap. Tetrahedron Comput Methodol 3:615–633