In Vitro Cellular Uptake, Distribution, and Metabolism of Oligonucleotides

Author:

Crooke R. M.

Publisher

Springer Berlin Heidelberg

Reference133 articles.

1. Aguilar L, Hemar A, Dautry-Varsat A, Blumenfeld M (1996) Hairpin, dumbbell, and single-stranded phosphodiester oligonucleotides exhibit identical uptake in T lymphocyte cell lines. Antisense Nucleic Acid Drug Dey 6:157–163

2. Akhtar S, Juliano RL (1992) Cellular uptake and intracellular fate of antisense oligonucleotides. Trends Cell Biol 2:139–144

3. Akhtar S, Basu S, Wickstrom E, Juliano RL (1991) Interactions of antisense DNA oligonucleotide analogs with phospholipid membranes (liposomes). Nucleic Acids Res 19:555–5559

4. Akhtar S, Shoji Y, Juliano RL (1992) Pharmaceutical aspects of the biological stability and membrane transport characteristics of antisense oligonucleotides. In: Erickson RP, Izant JG (eds) Gene regulation: biology of antisense RNA and DNA. Raven, New York, pp 133–145

5. Akhtar S, Beck GF, Hawley P, Irwin WJ, Gibson I (1996) The influence of polarized epithelial (Caco-2) cell differentiation on the cellular binding of phosphodiester and phosphorothioate oligonucleotides. Antisense Res Dev 6:19–206

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