Synthesis and Controlled Release of 5-Fluorouracil from Hydroxyethylchitosan: Based Polymer Prodrug

Author:

Peng Yanfei,Liu Wanshun,Han Baoqin,Zhou Ruixue

Publisher

Springer Berlin Heidelberg

Reference18 articles.

1. Nichifora M, Schachta EH, Seymour LW (1997) Polymeric prodrugs of 5-fluorouracil. J Control Release 48:165–178

2. Akashi M, Takemoto K (1990) New aspects of polymer drugs. Adv Polymer Sci 97:108–146

3. Ouchi T, Fujino A, Tanaka K et al (1990) Synthesis and antitumor activity of conjugates of poly(α-malic acid) and 5-fluorouracil bound via ester, amide or carbamoyl bonds. J Control Release 12:143–153

4. Ouchi T, Hagihara Y, Takahashi K et al (1992) Synthesis and anti-tumor activity of poly(ethylene glycol)s linked to 5-fluorouracil via urethane or urea bonds. Drug Design Disc 9:93–105

5. Ouchi T, Banba T, Matsumoto T et al (1990) Synthesis and anti-tumor activity of conjugates of 5-fluorouracil and chito-oligosaccharides involving a hexamethylene spacer group and carbamoyl bonds. Drug Design Del 6:281–287

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