The role of radiotherapy in adult soft tissues sarcoma of the extremities
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Published:2021-05-06
Issue:8
Volume:31
Page:1583-1596
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ISSN:1633-8065
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Container-title:European Journal of Orthopaedic Surgery & Traumatology
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language:en
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Short-container-title:Eur J Orthop Surg Traumatol
Author:
Cammelli SilviaORCID, Cortesi Annalisa, Buwenge Milly, Zamagni Alice, Ferioli Martina, Ghigi Giulia, Romeo Antonino, Morganti Alessio G.
Abstract
AbstractLocal management of adult soft tissue sarcoma of the extremities has evolved over the past decades. Until the 1970s, radical surgery (amputations) was the standard therapeutic procedure resulting in significant physical and psychological morbidity for the patients. In the present era, limb sparing surgery combined with radiotherapy represents the current standard of care for high grade and > 5 cm STSs. This approach guarantees high local control rate and function preservation. The aim of this paper is to summarize the current evidence for RT in STSs of the extremities. Outcomes, technical details (techniques, timing, dose, volumes of treatment) and the emerging role of RT in the management of oligometastatic disease will be analysed. Finally, results of the recent clinical trials testing new scenarios in RT of STSs will be described.
Funder
Alma Mater Studiorum - Università di Bologna
Publisher
Springer Science and Business Media LLC
Subject
Orthopedics and Sports Medicine,Surgery
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