Organ-specific biotransformation of ormaplatin in the Fischer 344 rat

Author:

Charles Thompson D.,Vaisman Alexandra,Sakata Michael K.,Wyriok Steven D.,Holbrook David J.,Chaney Stephen G.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference41 articles.

1. Anderson WK, Quagliato DA, Haugwitz RD, Narayanan VL, Wolpert-DeFilippes MK (1986) Synthesis, physical properties, and antitumor activity of tetraplatin and related tetrachloroplatinum(IV) stereoisomers of 1,2-diaminocyclohexane. Cancer Treat Rep 70:997

2. Blisard KS, Harrington DA, Long DA, Jackson JE (1991) Relative lack of toxicity of transplatin compared with cisplatin in rodents. J Comp Pathol 105:367

3. Borch RF (1987) The platinum anti-tumour drugs. In: Powis G, Prough RA (eds) Metabolism and action of anti-cancer drugs. Taylor & Francis, New York, p 163

4. Borch RF, Markman M (1989) Biochemical modulation of cisplatin toxicity. Pharmacol Ther 41:371

5. Carfagna PF, Chaney SG, Chang J, Holbrook DJ (1990) Reduction of tetrachloro(d,l-trans)1,2-diaminocyclohexaneplatinum(IV) (tetraplatin) toxicity by the administration of diethyldithiocarbamate (DDTC), S-2(3-aminopropylamino) ethylphosphorothioic acid (WR-2721), or sodium selenite in the Fischer 344 rat. Fundam Appl Toxicol 14:706

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3. High-performance liquid chromatographic separation of the biotransformation products of oxaliplatin;Journal of Chromatography B: Biomedical Sciences and Applications;1999-03

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