Cytotoxicity, DNA cross-linking, and DNA single-strand breaks induced by cyclophosphamide in a rat leukemia in vivo

Author:

Wang Ji-Yi,Prorok Greg,Vaughan William P.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference49 articles.

1. Ataya KM, Valeriote FA, Ramahi-Ataya AJ (1989) Effect of cyclophosphamide on the immature rat ovary. Cancer Res 49: 1660?1664

2. Benson AJ, Martin CN, Garner RC (1988)N-(2-Hydroxyethyl)-N-[2-(7-guaninyl)ethyl], the putative major DNA adduct of cyclophosphamide in vitro and in vivo in the rat. Biochem Pharmacol 37: 2979?2985

3. Bradley MO, Kohn KW (1979) X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution. Nucleic Acids Res 7: 793?804

4. Chetsanga CJ, Polidori G, Mainwaring M (1982) Analysis and excision of ring-opened phosphoramide mustard-deoxyguanine adducts in DNA. Cancer Res 42: 2616?2621

5. Colvin M, Chabner BA (1990) Alkylating agents. In: Chabner BA, Collins JM (eds) Cancer chemotherapy: principles and practice, J. B. Lippincott, Philadelphia, pp 276?313

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