Incidental Findings with Genomic Testing: Implications for Genetic Counseling Practice

Author:

Roche Myra I.,Berg Jonathan S.

Funder

National Center for Genome Research

NCTraCS

Publisher

Springer Science and Business Media LLC

Subject

General Medicine

Reference89 articles.

1. •• Kohane IS, Masys DR, Altman RB. The incidentalome: a threat to genomic medicine. JAMA. 2006;296(2):212–5. An early articulation of many concerns related to the potential for genomic incidental findings to derail genomic medicine.

2. Wolf SM, Lawrenz FP, Nelson CA, Kahn JP, Cho MK, Clayton EW, et al. Managing incidental findings in human subjects research: analysis and recommendations. J Law Med Ethics. 2007;36(2):219.

3. Christenhusz GM, Devriendt K, Dierickx K. Secondary variants-in defense of a more fitting term in the incidental findings debate. Eur J Hum Genet. 2013;21(12):1331–4.

4. •• Presidential Commission for the Study of Bioethical Issues. Anticipate and communicate: ethical management of incidental and secondary findings in the clinical, research, and direct-to-consumer contexts. Presidential Commission for the Study of Bioethical Issues. 2013. http://bioethics.gov/node/3183 Accessed 2 June 2015. A landmark paper that establishes recommended terminology and for incidental and secondary findings, and proposes pragmatic approaches to dealing with the possibility of incidental findings.

5. Netzer C, Klein C, Kohlhase J, Kubisch C. New challenges for informed consent through whole genome array testing. J Med Genet. 2009;46(7):495–6.

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