Alternative Approaches in Gene Discovery and Characterization in Alzheimer’s Disease
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Medicine
Link
http://link.springer.com/content/pdf/10.1007/s40142-013-0007-5.pdf
Reference131 articles.
1. Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, Collins FS, Manolio TA. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A. 2009;106:9362–7.
2. • Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, McCarthy MI, Ramos EM, Cardon LR, Chakravarti A, et al. Finding the missing heritability of complex diseases. Nature. 2009;461:747–53. This review article summarizes potential sources of heritability for human diseases and traits, which is not explained by GWAS variants, and discusses alternative approaches for discovering the sources for this “missing heritability”.
3. • Ertekin-Taner N. Gene expression endophenotypes: a novel approach for gene discovery in Alzheimer’s disease. Mol Neurodegener. 2011;6:31. This review article provides a detailed summary of gene expression GWAS studies in human tissues.
4. Gottesman II, Shields J. Genetic theorizing and schizophrenia. Br J Psychiatry. 1973;122:15–30.
5. Bearden CE, Freimer NB. Endophenotypes for psychiatric disorders: ready for primetime? Trends Genet. 2006;22:306–13.
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