Evaluating the Integration of Genomics into Cancer Screening Programmes: Challenges and Opportunities
Author:
Funder
Medical Research Council
Wellcome Trust
Publisher
Springer Science and Business Media LLC
Subject
General Medicine
Link
http://link.springer.com/content/pdf/10.1007/s40142-019-00162-x.pdf
Reference67 articles.
1. •• Turnbull C, Sud A, Houlston RS. Cancer genetics, precision prevention and a call to action. Nat Genet. 2018;50(9):1212–8. https://doi.org/10.1038/s41588-018-0202-0 . This paper provides a comprehensive review of cancer genetics including high and moderate risk cancer susceptibility genes and polygenic risk scores. It summarises the clinical utility of identifying variants in this genetic architecture and provides a call to action for population testing.
2. Lee A, Mavaddat N, Wilcox AN, Cunningham AP, Carver T, Hartley S, et al. BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors. Genet Med. 2019. https://doi.org/10.1038/s41436-018-0406-9 .
3. Frampton MJ, Law P, Litchfield K, Morris EJ, Kerr D, Turnbull C, et al. Implications of polygenic risk for personalised colorectal cancer screening. Ann Oncol. 2015;27:429–34. https://doi.org/10.1093/annonc/mdv540 .
4. Pashayan N, Duffy SW, Chowdhury S, Dent T, Burton H, Neal DE, et al. Polygenic susceptibility to prostate and breast cancer: implications for personalised screening. Br J Cancer. 2011;104(10):1656–63. https://doi.org/10.1038/bjc.2011.118 .
5. •• Torkamani A, Wineinger NE, Topol EJ. The personal and clinical utility of polygenic risk scores. Nat Rev Genet. 2018;19(9):581–90. https://doi.org/10.1038/s41576-018-0018-x . This is a recent and comprehensive reiview of the evidence supporting the clinical and personal utlitity of polygenic risk profiling.
Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Ethical, legal, and social implications of genetic risk prediction for multifactorial disease: a narrative review identifying concerns about interpretation and use of polygenic scores;Journal of Community Genetics;2022-12-19
2. Interest in genetic testing and risk-reducing behavioral changes: results from a community health assessment in New York City;Journal of Community Genetics;2022-10-13
3. Towards Better Pharmaceutical Provision in Europe—Who Decides the Future?;Healthcare;2022-08-22
4. Informed choice and attitudes regarding a genomic test to predict risk of colorectal cancer in general practice;Patient Education and Counseling;2021-08
5. Understanding polygenic models, their development and the potential application of polygenic scores in healthcare;Journal of Medical Genetics;2020-05-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3