Population pharmacokinetics and pharmacodynamics of efmarodocokin alfa (IL-22Fc)
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology
Link
https://link.springer.com/content/pdf/10.1007/s10928-023-09888-2.pdf
Reference30 articles.
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2. Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R (2004) IL-22 increases the innate immunity of tissues. Immunity 21(2):241–254. https://doi.org/10.1016/j.immuni.2004.07.007
3. Stefanich EG, Rae J, Sukumaran S, Lutman J, Lekkerkerker A, Ouyang W, Wang X, Lee D, Danilenko DM, Diehl L, Loyet KM, Herman A (2018) Pre-clinical and translational pharmacology of a human interleukin-22 IgG fusion protein for potential treatment of infectious or inflammatory diseases. Biochem Pharmacol 152:224–235. https://doi.org/10.1016/j.bcp.2018.03.031
4. Rae J, Hackney J, Huang K, Keir M, Herman A (2021) Identification of an IL-22-dependent gene signature as a pharmacodynamic biomarker. Int J Mol Sci. https://doi.org/10.3390/ijms22158205
5. Zheng Y, Valdez PA, Danilenko DM, Hu Y, Sa SM, Gong Q, Abbas AR, Modrusan Z, Ghilardi N, de Sauvage FJ, Ouyang W (2008) Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens. Nat Med 14(3):282–289. https://doi.org/10.1038/nm1720
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