Mechanism-based PK–PD model for the prolactin biological system response following an acute dopamine inhibition challenge: quantitative extrapolation to humans

Author:

Stevens Jasper,Ploeger Bart A.,Hammarlund-Udenaes Margareta,Osswald Gunilla,van der Graaf Piet H.,Danhof Meindert,de Lange Elizabeth C. M.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Reference39 articles.

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2. Movin-Osswald G, Hammarlund-Udenaes M (1995) Prolactin release after remoxipride by an integrated pharmacokinetic–pharmacodynamic model with intra- and interindividual aspects. J Pharmacol Exp Ther 274:921–927

3. Freeman ME, Kanyicska B, Lerant A, Nagy G (2000) Prolactin: structure, function, and regulation of secretion. Physiol Rev 80:1523–1631

4. Bagli M, Suverkrup R, Quadflieg R, Hoflich G, Kasper S, Moller HJ, Langer M, Barlage U, Rao ML (1999) Pharmacokinetic–pharmacodynamic modeling of tolerance to the prolactin-secreting effect of chlorprothixene after different modes of drug administration. J Pharmacol Exp Ther 291:547–554

5. Friberg LE, Vermeulen AM, Petersson KJF, Karlsson MO (2008) An agonist-antagonist interaction model for prolactin release following risperidone and paliperidone treatment. Clin Pharmacol Ther 85:409–417

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