Investigating the contribution of residual unexplained variability components on bias and imprecision of parameter estimates in population pharmacokinetic mixed-effects modeling
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology
Link
https://link.springer.com/content/pdf/10.1007/s10928-022-09837-5.pdf
Reference15 articles.
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2. Wang J, Gao P, Zhang H et al (2020) Evaluation of concentration errors and inappropriate dose tailoring of tacrolimus caused by sampling-time deviations in pediatric patients with primary nephrotic syndrome. Ther Drug Monit 42:392–399. https://doi.org/10.1097/FTD.0000000000000717
3. Santalo O, Baig U, Poulakos M, Brown D (2016) Early vancomycin concentrations and the applications of a pharmacokinetic extrapolation method to recognize sub-therapeutic outcomes. Pharmacy 4:37. https://doi.org/10.3390/pharmacy4040037
4. Proost JH (2019) Calculation of the coefficient of variation of log-normally distributed parameter values. Clin Pharmokinet 58:1101–1102
5. Baron KT (2022) mrgsolve: simulate from ODE-based models
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