Improving the estimation of parameter uncertainty distributions in nonlinear mixed effects models using sampling importance resampling

Author:

Dosne Anne-Gaëlle,Bergstrand Martin,Harling Kajsa,Karlsson Mats O.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Reference38 articles.

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2. Jonsson EN, Sheiner LB (2002) More efficient clinical trials through use of scientific model-based statistical tests. Clin Pharmacol Ther 72(6):603–614. doi: 10.1067/mcp.2002.129307

3. Kraiczi H, Frisen M (2005) Effect of uncertainty about population parameters on pharmacodynamics-based prediction of clinical trial power. Contemp Clini Trials 26(2):118–130. doi: 10.1016/j.cct.2004.10.002

4. Santen G, Danhof M, Pasqua OD (2008) Uncertainty and decision making in clinical development: the impact of an interim analysis based on the posterior predictive power on depression trials. http://tucson2008.go-acop.org/pdfs/DellaPasqua2.pdf . Accessed 16 Mar 2015

5. Waterhouse T, Benson C, Chiang A, Tang C (2009) Using uncertainty in exposure-response modeling and simulation to select phase II doses. http://2009.go-acop.org/sites/all/assets/webform/Waterhouse%20ACOP%202009%20poster.pdf . Accessed 2015 Mar 16

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