Benchmarking renin suppression and blood pressure reduction of direct renin inhibitor imarikiren through quantitative systems pharmacology modeling-Reference-Cited by-同舟云学术

Benchmarking renin suppression and blood pressure reduction of direct renin inhibitor imarikiren through quantitative systems pharmacology modeling

Published:2018-11-16 Issue:1 Volume:46 Page:15-25
ISSN:1567-567X
Container-title:Journal of Pharmacokinetics and Pharmacodynamics
language:en
Short-container-title:J Pharmacokinet Pharmacodyn

Author:

Gebremichael Yeshitila^ORCID,Lahu Gezim,Vakilynejad Majid,Hallow K. Melissa

Funder

Takeda Pharmaceuticals U.S.A.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Link

http://link.springer.com/article/10.1007/s10928-018-9612-y/fulltext.html

Reference25 articles.

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2. Campbell DJ (2008) Critical review of prorenin and (pro)renin receptor research. Hypertension 51(5):1259–1264. https://doi.org/10.1161/HYPERTENSIONAHA.108.110924

3. Mochel JP, Danhof M (2015) Chronobiology and pharmacologic modulation of the renin-angiotensin-aldosterone system in dogs: what have we learned? Rev Physiol Biochem Pharmacol 169:43–69. https://doi.org/10.1007/112_2015_27

4. Fyhrquist F, Metsarinne K, Tikkanen I (1995) Role of angiotensin II in blood pressure regulation and in the pathophysiology of cardiovascular disorders. J Hum Hypertens 9(Suppl 5):S19–S24

5. Mehta PK, Griendling KK (2007) Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. Am J Physiol Cell Physiol 292(1):C82–C97. https://doi.org/10.1152/ajpcell.00287.2006

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