Modeling and simulation of the exposure–response and dropout pattern of guanfacine extended-release in pediatric patients with ADHD

Author:

Knebel William,Rogers Jim,Polhamus Dan,Ermer James,Gastonguay Marc R.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Reference27 articles.

1. National Institute of Mental Health (2008) Attention Deficit Hyperactivity Disorder (ADHD), 08-3572 edn. US Department of Health and Human Services

2. Biederman J, Faraone SV (2005) Attention-deficit hyperactivity disorder. Lancet 366:237–248

3. Wolraich M, Brown L, Brown RT, et al (2011) Implementing the key action statements: an algorithm and explanation for process of care for the evaluation, diagnosis, treatment, and monitoring of ADHD in children and adolescents. Pediatrics 128:SI1–SI21

4. INTUNIV® (guanfacine) extended-release tablets [package insert]

5. Roberts MS, Nucifora KA, Braithwaite RS (2010) Using mechanistic models to simulate comparative effectiveness trials of therapy and to estimate long-term outcomes in HIV care. Med Care 48:S90–S95

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