First dose in children: physiological insights into pharmacokinetic scaling approaches and their implications in paediatric drug development
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology
Link
http://www.springerlink.com/index/pdf/10.1007/s10928-012-9241-9
Reference21 articles.
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2. Edginton AN, Schmitt W, Willmann S (2006) Development and evaluation of a generic physiologically based pharmacokinetic model for children. Clin Pharmacokinet 45:1013–1034
3. Nestorov I (2003) Whole body pharmacokinetic models. Clin Pharmacokinet 42:883–908
4. Johnson TN, Rostami-Hodjegan A, Tucker GT (2006) Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children. Clin Pharmacokinet 45:931–956
5. West GB, Brown JH, Enquist BJ (1997) A general model for the origin of allometric scaling laws in biology. Science 276:122–126
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