Mechanism-based disease progression modeling of type 2 diabetes in Goto-Kakizaki rats
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology
Link
http://link.springer.com/content/pdf/10.1007/s10928-010-9182-0.pdf
Reference49 articles.
1. CDC (2007) US Centers for Disease Control and Prevention (CDC): national diabetes fact sheet. CDC, Atlanta
2. Saltiel AR, Kahn CR (2001) Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414:799–806
3. LeRoith D (2002) Beta-cell dysfunction and insulin resistance in type 2 diabetes: role of metabolic and genetic abnormalities. Am J Med 113(Suppl 6A):3S–11S
4. Chan PL, Holford NH (2001) Drug treatment effects on disease progression. Annu Rev Pharmacol Toxicol 41:625–659
5. Portha B (2005) Programmed disorders of beta-cell development and function as one cause for type 2 diabetes? The GK rat paradigm. Diabetes Metab Res Rev 21:495–504
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