Kinetics of drug action in disease states: towards physiology-based pharmacodynamic (PBPD) models

Author:

Danhof Meindert

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Reference123 articles.

1. Kato R (1977) Drug metabolism under pathological and abnormal physiological states in animals and man. Xenobiotica 7(1–2):25–92

2. Koch-Weser J (1972) Drug therapy. serum drug concentrations as therapeutic guides. N Engl J Med 287(5):227–231. doi: 10.1056/NEJM197208032870505

3. Levy G (1974) Clinical pharmacokinetics. Academy of Pharmaceutical Sciences, Washington

4. Evans WES, Jerome J, Jusko WJ (1980) Applied pharmacokinetics: principles of therapeutic drug monitoring. Applied Therapeutics Inc., San Francisco, vol 3. Biopharmaceutics & Drug Disposition, Wiley. doi: 10.1002/bdd.2510030315

5. Danhof M, Levy G (1984) Kinetics of drug action in disease states. I. Effect of infusion rate on phenobarbital concentrations in serum, brain and cerebrospinal fluid of normal rats at onset of loss of righting reflex. J Pharmacol Exp Ther 229(1):44–50

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