Comparing the performance of first-order conditional estimation (FOCE) and different expectation–maximization (EM) methods in NONMEM: real data experience with complex nonlinear parent-metabolite pharmacokinetic model
Author:
Funder
National Institutes of Health
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology
Link
https://link.springer.com/content/pdf/10.1007/s10928-021-09753-0.pdf
Reference17 articles.
1. Sheiner LB, Beal SL (1980) Evaluation of methods for estimating population pharmacokinetics parameters. I. Michaelis-Menten model: routine clinical pharmacokinetic data. J Pharmacokinet Biopharm 8(6):553–571. https://doi.org/10.1007/BF01060053
2. Beal S, Sheiner L (1998) NONMEM users guide-Part VII: Conditional estimation methods. NONMEM Project Group, San Francisco
3. Bauer RJ (2017) NONMEM users guide-Introduction to NONMEM 7.4.1. ICON Plc, Dublin
4. Bauer RJ, Guzy S, Ng C (2007) A survey of population analysis methods and software for complex pharmacokinetic and pharmacodynamic models with examples. AAPS J 9(1):E60-83. https://doi.org/10.1208/aapsj0901007
5. Gibiansky L, Gibiansky E, Bauer R (2012) Comparison of Nonmem 7.2 estimation methods and parallel processing efficiency on a target-mediated drug disposition model. J Pharmacokinet Pharmacodyn 39(1):17–35. https://doi.org/10.1007/s10928-011-9228-y
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