Coping with time scales in disease systems analysis: application to bone remodeling

Author:

Schmidt Stephan,Post Teun M.,Peletier Lambertus A.,Boroujerdi Massoud A.,Danhof Meindert

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Reference47 articles.

1. Chan PL, Holford NH (2001) Drug treatment effects on disease progression. Annu Rev Pharmacol Toxicol 41:625–659

2. Danhof M, de Jongh J, De Lange EC, Della Pasqua O, Ploeger BA, Voskuyl RA (2007) Mechanism-based pharmacokinetic-pharmacodynamic modeling: biophase distribution, receptor theory, and dynamical systems analysis. Annu Rev Pharmacol Toxicol 47:357–400

3. Post TM, Freijer JI, DeJongh J, Danhof M (2005) Disease system analysis: basic disease progression models in degenerative disease. Pharm Res 22:1038–1049

4. Schmidt S, Post TM, Boroujerdi MA, van Kesteren C, Ploeger BA, Della Pasqua OE, Danhof M (2010) Disease progression analysis: towards mechanism-based models. In: Kimko HC, Peck CC (eds) Clinical trial simulations, 1st edn. Springer, New York, pp 437–459

5. Post TM (2009) Disease system analysis: between complexity and (over)simplification. Dissertation, Leiden University

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