Population in vitro–in vivo pharmacokinetic model of first-pass metabolism: itraconazole and hydroxy-itraconazole
Author:
Funder
Science and Industry Endowment Fund (AU)
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology
Link
http://link.springer.com/article/10.1007/s10928-017-9555-8/fulltext.html
Reference29 articles.
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2. Hennig S, Wainwright CE, Bell SC, Miller H, Friberg LE, Charles BG (2006) Population pharmacokinetics of itraconazole and its active metabolite hydroxy-itraconazole in paediatric cystic fibrosis and bone marrow transplant patients. Clin Pharmacokinet 45(11):1099–1114
3. Koks CH, Huitema AD, Kroon ED, Chuenyam T, Sparidans RW, Lange JM, Beijnen JH (2003) Population pharmacokinetics of itraconazole in Thai HIV-1-infected persons. Ther Drug Monit 25(2):229–233
4. Abuhelwa AY, Foster DJ, Mudge S, Hayes D, Upton RN (2015) Population pharmacokinetic modeling of itraconazole and hydroxyitraconazole for oral SUBA-itraconazole and sporanox capsule formulations in healthy subjects in fed and fasted states. Antimicrob Agents Chemother 59(9):5681–5696. https://doi.org/10.1128/AAC.00973-15
5. Grant SM, Clissold SP (1989) Itraconazole. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in superfecial and systemic mycoses. Drugs 37(3):310–344
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