Target-mediated pharmacokinetic and pharmacodynamic model of recombinant human erythropoietin (rHuEPO)

Author:

Woo Sukyung,Krzyzanski Wojciech,Jusko William J.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Reference49 articles.

1. Koury MJ, Sawyer ST and Brandt SJ (2002). New insights into erythropoiesis. Curr Opin Hematol 9: 93–100

2. Walrafen P, Verdier F, Kadri Z, Chretien S, Lacombe C and Mayeux P (2005). Both proteasomes and lysosomes degrade the activated erythropoietin receptor. Blood 105: 600–608

3. Chapel S, Veng-Pedersen P, Hohl RJ, Schmidt RL, McGuire EM and Widness JA (2001). Changes in erythropoietin pharmacokinetics following busulfan-induced bone marrow ablation in sheep: evidence for bone marrow as a major erythropoietin elimination pathway. J Pharmacol Exp Ther 298: 820–824

4. Kato M, Kamiyama H, Okazaki A, Kumaki K, Kato Y and Sugiyama Y (1997). Mechanism for the nonlinear pharmacokinetics of erythropoietin in rats. J Pharmacol Exp Ther 283: 520–527

5. Jin F and Krzyzanski W (2004). Pharmacokinetic model of target-mediated disposition of thrombopoietin. AAPS PharmSci 6: 1–8

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