Comparison of monoclonal antibody disposition predictions using different physiologically based pharmacokinetic modelling platforms
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology
Link
https://link.springer.com/content/pdf/10.1007/s10928-023-09894-4.pdf
Reference39 articles.
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2. Shah DK, Betts AM (2013) Antibody biodistribution coefficients. MAbs 5:297–305. https://doi.org/10.4161/mabs.23684
3. Glassman PM, Abuqayyas L, Balthasar JP (2015) Assessments of antibody biodistribution. J Clin Pharmacol 55:S29–S38. https://doi.org/10.1002/jcph.365
4. Garg A, Balthasar JP (2007) Physiologically-based pharmacokinetic (PBPK) model to predict IgG tissue kinetics in wild-type and FcRn-knockout mice. J Pharmacokinet Pharmacodyn 34:687–709. https://doi.org/10.1007/s10928-007-9065-1
5. Lobo ED, Hansen RJ, Balthasar JP (2004) Antibody pharmacokinetics and pharmacodynamics. J Pharm Sci 93:2645–2668. https://doi.org/10.1002/jps.20178
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1. A minimal physiologically based pharmacokinetic model to study the combined effect of antibody size, charge, and binding affinity to FcRn/antigen on antibody pharmacokinetics;Journal of Pharmacokinetics and Pharmacodynamics;2024-02-24
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