Population pharmacokinetics and pharmacodynamics of IONIS-GCGRRx, an antisense oligonucleotide for type 2 diabetes mellitus: a red blood cell lifespan model-Reference-Cited by-同舟云学术

Population pharmacokinetics and pharmacodynamics of IONIS-GCGRRx, an antisense oligonucleotide for type 2 diabetes mellitus: a red blood cell lifespan model

Published:2017-01-28 Issue:3 Volume:44 Page:179-191
ISSN:1567-567X
Container-title:Journal of Pharmacokinetics and Pharmacodynamics
language:en
Short-container-title:J Pharmacokinet Pharmacodyn

Author:

Luu Kenneth T.^ORCID,Morgan Erin S.,Bhanot Sanjay,Geary Richard,Smith Anne,Bethune Claudette,Watts Lynnetta,Henry Scott,Wang Yanfeng

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Link

http://link.springer.com/article/10.1007/s10928-017-9505-5/fulltext.html

Reference24 articles.

1. Crooke ST, Vickers T, Lima WF, Wu H (2007) Mechanisms of antisense drug action, an introduction. CRC Press, Boca Raton

2. Geary RS, Norris D, Yu R, Bennett CF (2015) Pharmacokinetics, biodistribution and cell uptake of antisense oligonucleotides. Adv Drug Deliv Rev. 87:46–51

3. Bennett CF, Swayze EE (2010) RNA targeting therapeutics: molecular mechanisms of antisense oligonucleotides as a therapeutic platform. Annu Rev Pharmacol Toxicol 50:259–293

4. McKay RA, Miraglia LJ, Cummins LL, Owens SR, Sasmor H, Dean NM (1999) Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-alpha expression. J Biol Chem 274(3):1715–1722

5. Geary RS, Yu RZ, Watanabe T et al (2003) Pharmacokinetics of a tumor necrosis factor-alpha phosphorothioate 2′-O-(2-methoxyethyl) modified antisense oligonucleotide: comparison across species. Drug Metab Dispos 31(11):1419–1428

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