A framework for 2-stage global sensitivity analysis of GastroPlus™ compartmental models

Author:

Scherholz Megerle L.,Forder James,Androulakis Ioannis P.

Funder

Bristol-Myers Squibb

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Reference70 articles.

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2. Chen GC, Enayati P, Tran T, Lee-Henderson M, Quan C, Dulai G, Arnott I, Sul J, Jutabha R (2006) Sensitivity and inter-observer variability for capsule endoscopy image analysis in a cohort of novice readers. World J Gastroenterol 12(8):1249–1254. https://doi.org/10.3748/wjg.v12.i8.1249

3. Strategies, approaches, and challenges in model-informed drug development (MIDD) (2017). FDA briefing document—Pharmaceutical Science and Clinical Pharmacology Advisory Committee meeting, Rockville, MD

4. WHO (2010) Harmonization project document no. 9: characterization and application of physiologically based pharmacokinetic models in risk assessment. World Health Organization International Programme on Chemical Safety Harmonization Project, Ottawa, ON

5. McNally K, Cotton R, Loizou GD (2011) A workflow for global sensitivity analysis of PBPK models. Front Pharmacol 2:31. https://doi.org/10.3389/fphar.2011.00031

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