A phase 1 pooled PK/PD analysis of bone resorption biomarkers for odanacatib, a Cathepsin K inhibitor
Author:
Funder
Merck
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology
Link
https://link.springer.com/content/pdf/10.1007/s10928-020-09699-9.pdf
Reference31 articles.
1. Bone HG, Dempster DW, Eisman JA, Greenspan SL, McClung MR, Nakamura T, Papapoulos S, Shih WJ, Rybak-Feiglin A, Santora AC, Verbruggen N, Leung AT, Lombardi A (2015) Odanacatib for the treatment of postmenopausal osteoporosis: development history and design and participant characteristics of LOFT, the long-term odanacatib fracture trial. Osteoporos Int 26(2):699–712
2. Stone JA, McCrea JB, Witter R, Zajic S, Stoch SA (2019) Clinical and translational pharmacology of the cathepsin K inhibitor odanacatib studied for osteoporosis. Br J Clin Pharmacol 85(6):1072–1083
3. Armas LAG, Recker RR (2012) Pathophysiology of osteoporosis. Endocrinol Metab Clin North Am 41(3):475–486
4. Charles JF, Aliprantis AO (2014) Osteoclasts: more than ‘bone eaters’. Trends Mol Med 20(8):449–459
5. Inaoka T, Bilbe G, Ishibashi O, Tezuka K, Kumegawa M, Kokubo T (1995) Molecular cloning of human cDNA for Cathepsin K: novel cysteine proteinase predominantly expressed in bone. Biochem Biophys Res Commun 206(1):89–96
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