Rapid identification of elaiophylin and geldanamycin inStreptomyces fermentation broths using CPC coupled with a photodiode array detector and LC-MS methodologies

Author:

Alvi K A,Peterson J,Hofmann B

Publisher

Oxford University Press (OUP)

Subject

Applied Microbiology and Biotechnology,Applied Microbiology and Biotechnology,Biotechnology,Bioengineering

Reference6 articles.

1. Fiedler H-P. 1993. Screening for secondary metabolites by HPLC and UV-visible absorbance spectral libraries. Nat Prod Lett 2: 119–128.

2. Huber L and H-P Fielder. 1991. HPLC with computerized diode-array detection in pharmaceutical research. In: HPLC in the Pharmaceutical Industry (Fong GW and SK Lam, eds), pp 123–146, Marcel Dekker, New York.

3. Kaiser H and W Keller-Schierlein. 1981. Structure elucidation of elaiophylin: spectroscopy and chemical degradation. Helv Chim Acta 64: 407–424.

4. Kazuya S, KL Rinehart Jr, G Slomp, MF Grostic and EC Olson. 1970. Geldanamycin. I. Structure assignment. J Amer Chem Soc 92: 7591–7593.

5. Mierzwa R, J Marquez, M Patel and R Cooper. 1989. HPLC detection methods for microbial products in fermentation broth. In: Natural Products Isolation (Wagman GW and R Cooper, eds), Ch 2, Elsevier, Amsterdam.

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