Applying the Functional Luminal Imaging Probe to Esophageal Disorders
Author:
Publisher
Springer Science and Business Media LLC
Subject
Gastroenterology,General Medicine
Link
http://link.springer.com/content/pdf/10.1007/s11894-020-0749-7.pdf
Reference31 articles.
1. McMahon BP, Frokjaer JB, Liao D, Kunwald P, Drewes AM, Gregersen H. A new technique for evaluating sphincter function in visceral organs: application of the functional lumen imaging probe (FLIP) for the evaluation of the oesophago-gastric junction. Physiol Meas. 2005;26(5):823–36.
2. Carlson DA, Lin Z, Kahrilas PJ, Sternbach J, Donnan EN, Friesen L, et al. The functional lumen imaging probe detects esophageal contractility not observed with manometry in patients with achalasia. Gastroenterology. 2015;149(7):1742–51.
3. Carlson DA, Lin Z, Rogers MC, Lin CY, Kahrilas PJ, Pandolfino JE. Utilizing functional lumen imaging probe topography to evaluate esophageal contractility during volumetric distention: a pilot study. Neurogastroenterol Motil. 2015;27(7):981–9.
4. •• Carlson DA, Kahrilas PJ, Lin Z, Hirano I, Gonsalves N, Listernick Z, et al. Evaluation of esophageal motility utilizing the functional lumen imaging probe. Am J Gastroenterol. 2016;111(12):1726–35 This study evaluated 145 patients with dysphagia with EGD, FLIP, and high-resolution esophageal manometry. FLIP topography identified 95% of patients with abnormal motility on manometry, including 100% of achalasia patients. FLIP topography was able to identify abnormalities not found on manometry.
5. •• Carlson DA, Kou W, Lin Z, Hinchcliff M, Thakrar A, Falmagne S, et al. Normal values of esophageal distensibility and distension-induced contractility measured by functional luminal imaging probe panometry. Clin Gastroenterol Hepatol. 2019;17(4):674–81 e1 This prospective study evaluated 20 asymptomatic volunteers with the FLIP to identify normal parameters of FLIP panometry. The normal EGJ-DI is greater than 2.8 mm2/mm Hg , distensibility plateau of greater than 18 mm and repetitive antegrade contractions are normal findings for esophageal distensibility and distension-induced contractility.
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